O2 Sensor Contamination
WARNING: This page does not describe the selected car, but rather 6 other vehicles, including the 1992 Pontiac Firebird, 1992 Oldsmobile Custom Cruiser, 1992 Chevrolet Caprice, 1992 Chevrolet Camaro, and 1992 Cadillac Brougham. However, it is still accessible from the selected car via links, so may be relevant.
O2 sensor contamination, caused by silicone in certain fuels or use of improper RTV sealant, may cause a white powdery coating to cover exterior of O2 sensor. False high signal voltage (low oxygen content sensed) produced is interpreted by control module as a rich mixture, causing control module to set Code 45.