O2 Sensor Contamination
WARNING: This page does not describe the selected car, but rather 24 other vehicles, including the 1993 Pontiac Trans Sport, 1993 Oldsmobile Silhouette, 1993 Oldsmobile Bravada, 1993 GMC Vandura, and 1993 GMC Value Van. However, it is still accessible from the selected car via links, so may be relevant.
O2 sensor contamination, caused by silicone in certain fuels or use of improper RTV sealant, may cause a White-powdery coating to cover O2 sensor. The false high signal voltage produced (or low oxygen content sensed) is interpreted by ECM as a rich mixture, causing ECM to set Code 45.